Technology Platform Nutraceutical Development BM-A1 Clinical Trial Therapeutic Development Publications

Proteomics As noted above, tissues and organs communicate primarily by expressing signaling proteins and exporting them through the bloodstream. Indeed, measuring the presence or the level of individual proteins in the blood is commonly used in medical diagnostic practice. At BioMarker, we apply time-of-flight protein chip mass spectrometry to characterize the presence and levels of the totality of proteins in the bloodstream. We can then correlate the levels of select proteins to our own database of genetic biomarkers of aging. This allows us an opportunity to perform the broadest possible biomarker analysis with the least invasive process. Using microarray gene chip technology, we can measure the levels of activity of all genes in a given type of cell. In diagnostic development, we focus on measurement of leukocytes, or white blood cells. These cells express many gene sets that have been shown to be differentially regulated in age-defying interventions such as calorie restriction, including genes relating especially to immune defense and to the regulation of processes such as inflammation.